For research purposes only — not for human consumption — 18+ only
Anti-Aging
GHK-Cu 50mg
$40.00
Copper peptide studied for skin regeneration wound healing collagen stimulation and anti-inflammatory properties.
GHK-Cu (Glycyl-L-Histidyl-L-Lysine copper complex) is a naturally occurring tripeptide-copper complex found in human plasma, saliva, and urine. First isolated by Loren Pickart in 1973, GHK-Cu has since been shown to modulate over 4,000 human genes involved in tissue remodelling, anti-inflammation, DNA repair, and stem cell activation — making it one of the most comprehensively studied naturally occurring peptides. Its concentration in plasma declines significantly with age, from approximately 200 ng/mL at age 20 to 80 ng/mL at age 60, correlating with declining tissue repair capacity.
Molecular Data
Sequence: Gly-His-Lys (complexed with Cu2+) | Molecular Formula: C14H24CuN6O4 | Molecular Weight: 403.90 g/mol | CAS Number: 89030-95-5
Collagen and Extracellular Matrix Synthesis
GHK-Cu is one of the most potent known stimulators of collagen synthesis, activating both collagen I and collagen III production in fibroblasts while simultaneously stimulating the production of elastin, proteoglycans, and glycosaminoglycans. This dual action — building new extracellular matrix components while remodelling damaged ones through matrix metalloproteinase activation — makes GHK-Cu uniquely effective as a tissue repair research tool.
Gene Expression Modulation
Perhaps GHK-Cu's most remarkable property is its broad gene regulatory activity. Studies using gene array analysis have shown that GHK-Cu modulates over 4,000 human genes — upregulating genes associated with tissue repair, anti-inflammation, and stem cell activation while downregulating genes associated with cancer progression, inflammation, and cellular degeneration. GHK-Cu appears to reset aged fibroblast gene expression toward a younger, more regenerative phenotype.
Wound Healing and Angiogenesis
GHK-Cu accelerates wound healing through multiple mechanisms: stimulating VEGF production to promote angiogenesis, activating TGF-β signalling to drive fibroblast proliferation, and upregulating fibronectin and laminin for scaffolding new tissue growth. In animal wound models, topical GHK-Cu consistently accelerates closure times and improves the quality of healed tissue compared to controls.
Hair Follicle and Neural Applications
Research demonstrates that GHK-Cu promotes hair follicle size and stimulates hair shaft elongation in vitro through activation of hair follicle stem cells. Additionally, GHK-Cu has shown neuroprotective properties in neuronal cell models, protecting against oxidative damage and promoting nerve growth factor expression — areas of emerging research interest.
Future Research
GHK-Cu research continues to expand with interest in its epigenetic regulatory mechanisms, potential anti-cancer properties (via inhibition of metastasis-related genes), and neurological applications. Its broad gene regulatory activity positions it as one of the most versatile peptides in research.
Product Usage
This product is intended as a research chemical only. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.
Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals.
This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabelled as a drug, food or cosmetic.
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